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The uncontrolled, combined presence of ROS, RNS, pro inflammatory cytokines, and reactive by-products of arachidonic acid "metabolism" result in "severe inflammatory response syndrome" that is found in non-bacterial sepsis states, and in serious viral infections such as smallpox, and influenza epidemics

For seed germination analyses, Arabidopsis seeds were surface sterilized and grown on half strength MS medium containing 1% sucrose in a climate chamber under long-day condition